时间：10月13日（周一）下午15：40

地点：勤园20-518

报告简介：

Spiral waves are widely found in various fields and have been demonstrated to exist in the human heart, where they are closely related to atrial fibrillation. The motion of phase singularities (PSs) that lie at the center of spiral waves captures many qualitative and, in some cases, quantitative features of their complex dynamics. Recent clinical studies suggested that ablating the tissue at PS locations may cure atrial fibrillation. However, identifying PSs remains challenging due to limitations in data resolution and the complex structure of the human heart. To address these challenges, we have conducted a series of studies to develop PS identification methods suitable for different scenarios. In two dimensions, we introduced a topological charge-density method that directly calculates the topological charge at each grid point, enabling precise PS localization. Extending this approach to three dimensions, we developed a topological charge-density vector method that not only locates scroll wave filaments but also reveals their direction passing through sections. For low-resolution data, we proposed a topological charge-weighted method that effectively reduces false points and enhances PS localization accuracy. These three studies not only hold significant theoretical importance but also provide guidance for the diagnosis and treatment of atrial fibrillation and other related diseases.

报告人简介：

何银杰，博士，2023年博士毕业于浙江大学，现任职于浙江工业大学之江学院，主要研究内容为心脏组织中螺旋波相奇点的定位与光遗传学控制。近五年来参与完成国家自然科学基金2项，其主要成果均以第一作者身份发表于Physical Review E，获浙江省科协青年人才托举培养项目支持。